Lsamp Gene Summary [Mouse]
Acts upstream of or within locomotory exploration behavior. Predicted to be located in cytosol. Is expressed in several structures, including alimentary system; integumental system; limb; nervous system; and sensory organ. Orthologous to human LSAMP (limbic system associated membrane protein). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Lsamp |
| Official Name | limbic system-associated membrane protein [Source:MGI Symbol;Acc:MGI:1261760] |
| Ensembl ID | ENSMUSG00000061080 |
| Bio databases IDs | |
| Aliases | limbic system-associated membrane protein |
| Synonyms | 5430428I19, AW046674, B130007O04Rik, D930023J12Rik, Gm29907, IGLON3, Lam, LAMP, limbic system-associated membrane protein |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lsamp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
- N-methyl-D-aspartate
- GATAD2B
- W7
disease
- neoplasia
- colorectal cancer
- Huntington disease
- insomnia
- lung cancer
- cytomegalovirus infection
- self-abusive behavior
- atrial premature complex
- epithelial ovarian cancer
- neuroticism
role in cell
- growth
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Extracellular Space
- cellular membrane
- cytosol
- presynaptic membrane
- postsynaptic membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lsamp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nervous system development
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- cytosol
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding