Rpl34 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation; translation at postsynapse; and translation at presynapse. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in cerebral cortex ventricular layer; cortical plate; and embryo. Orthologous to human RPL34 (ribosomal protein L34). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl34 |
| Official Name | ribosomal protein L34 [Source:MGI Symbol;Acc:MGI:1915686] |
| Ensembl ID | ENSMUSG00000062006 |
| Bio databases IDs | |
| Aliases | ribosomal protein L34 |
| Synonyms | 1100001I22RIK, eL34, L34, ribosomal protein L34, Rpl34l2, YB24H02 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl34 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- protein binding
- Ribosomal protein L34e
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl34 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metabolic syndrome X
- acute myeloid leukemia
- chronic kidney disease
regulates
- ERK1/2
role in cell
- survival
- phosphorylation in
- cell death
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- ribosome
- Endoplasmic Reticulum
- cytosol
- nucleoli
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl34 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- translation
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytosolic ribosome
- cytoplasm
- cytosol
- endoplasmic reticulum
- synapse
- cytosolic large ribosomal subunit
- nucleolus
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome
- cadherin binding