Lmtk3 Gene Summary [Mouse]

Predicted to enable protein kinase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in Golgi membrane; axon; and dendrite. Is expressed in liver lobe and nervous system. Orthologous to human LMTK3 (lemur tyrosine kinase 3). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Lmtk3
Official Name
lemur tyrosine kinase 3 [Source:MGI Symbol;Acc:MGI:3039582]
Ensembl ID
ENSMUSG00000062044
Bio databases IDs NCBI: 381983 Ensembl: ENSMUSG00000062044
Aliases lemur tyrosine kinase 3
Synonyms 5e5 antigen, AATYK3, lemur tyrosine kinase 3, LMR3, LOC691056, PPP1R101, TYKLM3
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lmtk3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • Serine/Threonine protein kinases, catalytic domain
  • Protein kinase (unclassified specificity)
  • Protein Kinases, catalytic domain
  • Protein tyrosine and serine/threonine kinase
  • protein binding
  • Protein kinase domain
  • protein-tyrosine kinase
  • Tyrosine kinase, catalytic domain

Pathways

Biological processes and signaling networks where the Lmtk3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hyperactive behavior
regulated by
regulates
role in cell
  • function
  • ciliogenesis in
  • morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • perinuclear Golgi regions
  • neurites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Lmtk3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein phosphorylation

Cellular Component

Where in the cell the gene product is active
  • dendrite
  • Golgi membrane
  • axon

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein binding
  • metal ion binding
  • protein kinase activity
  • protein serine/threonine kinase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.