Krt73 Gene Summary [Mouse]

Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be active in keratin filament. Is expressed in external naris and vibrissa. Orthologous to human KRT73 (keratin 73). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Krt73
Official Name
keratin 73 [Source:MGI Symbol;Acc:MGI:3607712]
Ensembl ID
ENSMUSG00000063661
Bio databases IDs NCBI: 223915 Ensembl: ENSMUSG00000063661
Aliases keratin 73
Synonyms CK-73, IRT6IRS3, K6IRS3, K73, Kb36, keratin 73, KRT6IRS3, LOC105369772
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Krt73 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ciliary protein causing Leber congenital amaurosis disease
  • Transforming acidic coiled-coil-containing protein (TACC), C-terminal
  • protein binding
  • Intermediate filament protein
  • Keratin type II head
  • Apolipoprotein A1/A4/E domain
  • FlgN protein

Pathways

Biological processes and signaling networks where the Krt73 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • androgenic alopecia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Krt73 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • keratinization
  • intermediate filament organization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • extracellular vesicular exosome
  • keratin filament
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • structural constituent of epidermis
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.