Il3ra Gene Summary [Mouse]
Predicted to enable interleukin-3 receptor activity. Acts upstream of or within interleukin-3-mediated signaling pathway. Predicted to be located in endomembrane system and plasma membrane. Is expressed in several structures, including bone marrow; cardiovascular system mesenchyme; dorsal aorta; early conceptus; and umbilical or vitelline vessel. Orthologous to human IL3RA (interleukin 3 receptor subunit alpha). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Il3ra |
| Official Name | interleukin 3 receptor, alpha chain [Source:MGI Symbol;Acc:MGI:96553] |
| Ensembl ID | ENSMUSG00000068758 |
| Bio databases IDs | |
| Aliases | interleukin 3 receptor, alpha chain |
| Synonyms | CD123, CDw123, interleukin 3 receptor, alpha chain, interleukin 3 receptor, α chain, SUT-1 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Il3ra often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- IL-3 receptor alpha chain N-terminal domain
- FN3
- interleukin-3 receptor
- transmembrane receptor
Pathways
Biological processes and signaling networks where the Il3ra gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane