Rps11 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; cortical plate; pancreas epithelium; and telencephalon. Orthologous to human RPS11 (ribosomal protein S11). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps11 |
| Official Name | ribosomal protein S11 [Source:MGI Symbol;Acc:MGI:1351329] |
| Ensembl ID | ENSMUSG00000003429 |
| Bio databases IDs | |
| Aliases | ribosomal protein S11 |
| Synonyms | BF448693, ribosomal protein S11, S11, uS17 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Ribosomal protein S17
- protein binding
- Ribosomal_S17 N-terminal
- ribosomal protein uS17, archaeal form
- rpsQ
Pathways
Biological processes and signaling networks where the Rps11 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-small cell lung cancer
- non-small cell lung carcinoma
role in cell
- expression in
- cell death
- cell viability
- processing in
- translation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pre-ribosome
- ribosome
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- ribosomal small subunit biogenesis
- translation
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- cytosolic ribosome
- cytosolic small ribosomal subunit
- synapse
- nucleolus
- ribosome
- nucleoplasm
- extracellular vesicular exosome
- focal adhesion
- cytoplasm
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- structural constituent of ribosome
- rRNA binding