Fibin Gene Summary [Mouse]

Enables protein homodimerization activity. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; hemolymphoid system gland; male reproductive gland or organ; musculoskeletal system; and skin. Orthologous to human FIBIN (fin bud initiation factor homolog). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fibin
Official Name
fin bud initiation factor homolog (zebrafish) [Source:MGI Symbol;Acc:MGI:1914856]
Ensembl ID
ENSMUSG00000074971
Bio databases IDs NCBI: 67606 Ensembl: ENSMUSG00000074971
Aliases fin bud initiation factor homolog (zebrafish)
Synonyms 1110018M03Rik, fin bud initiation factor homolog, fin bud initiation factor homolog (zebrafish)
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fibin often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Fin bud initiation factor homolog
  • protein homodimerization

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-small cell lung cancer
  • atherosclerosis
  • preeclampsia
  • hypertrophic scarring
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Endoplasmic Reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Fibin gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • response to manganese ion
  • protein kinase C signaling cascade
  • response to dexamethasone stimulus

Cellular Component

Where in the cell the gene product is active
  • Golgi apparatus
  • endoplasmic reticulum
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein homodimerization activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.