Aarsd1 Gene Summary [Mouse]
Enables Ser-tRNA(Ala) deacylase activity. Acts upstream of or within regulation of translational fidelity. Predicted to be located in cytoplasm. Is expressed in submandibular gland primordium. Orthologous to several human genes including AARSD1 (alanyl-tRNA synthetase domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Aarsd1 |
| Official Name | alanyl-tRNA synthetase domain containing 1 [Source:MGI Symbol;Acc:MGI:1916934] |
| Ensembl ID | ENSMUSG00000075528 |
| Bio databases IDs | |
| Aliases | alanyl-tRNA synthetase domain containing 1 |
| Synonyms | 1110069E20Rik, 2310044P18Rik, alanyl-tRNA synthetase domain containing 1, AlaX, AlaXp, AlaXp-II |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Aarsd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Threonyl and Alanyl tRNA synthetase second additional domain
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Aarsd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of translational fidelity
- alanyl-tRNA aminoacylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- nucleic acid binding
- ATP binding
- alanine-tRNA ligase activity
- metal ion binding
- Ser-tRNA(Ala) hydrolase activity