Sarnp Gene Summary [Mouse]
Enables chromatin binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; limb; oocyte; and retina. Orthologous to human SARNP (SAP domain containing ribonucleoprotein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Sarnp |
| Official Name | SAP domain containing ribonucleoprotein [Source:MGI Symbol;Acc:MGI:1913368] |
| Ensembl ID | ENSMUSG00000078427 |
| Bio databases IDs | |
| Aliases | SAP domain containing ribonucleoprotein |
| Synonyms | 1110005A23Rik, CIP29, HCC1, HSPC316, RGD1305692, SAP domain containing ribonucleoprotein, THO1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sarnp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- SAP motif
- SAP domain
- chromatin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytoplasmic ribonucleoprotein granule
- nucleoplasm
- nucleoli
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sarnp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of translation
- mRNA export from nucleus
- negative regulation of transcription from RNA polymerase II promoter
- poly(A)+ mRNA export from nucleus
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- transcription export complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- RNA binding
- protein binding
- chromatin binding