Evi2a Gene Summary [Mouse]
Predicted to be located in several cellular components, including Golgi apparatus; cilium; and cytosol. Is expressed in several structures, including central nervous system; heart; hemolymphoid system; and ureter. Orthologous to human EVI2A (ecotropic viral integration site 2A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Evi2a |
| Official Name | ecotropic viral integration site 2a [Source:MGI Symbol;Acc:MGI:95458] |
| Ensembl ID | ENSMUSG00000078771 |
| Bio databases IDs | |
| Aliases | ecotropic viral integration site 2a |
| Synonyms | ecotropic viral integration site 2A, EVDA, EVI2, LOC688044 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Evi2a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Ectropic viral integration site 2A protein (EVI2A)
- transmembrane receptor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- peripheral arterial disease
- glioblastoma
- glioblastoma cancer
- laser induced choroidal neovascularization
- endometrial carcinoma
- epithelial endometrial cancer
- paroxysmal nocturnal hemoglobinuria
- insulin-dependent diabetes mellitus
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- intracellular membrane-bounded organelle
- cilia
- cellular membrane
- Golgi Apparatus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Evi2a gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- transmembrane signaling receptor activity
- protein binding