Mia Gene Summary [Mouse]
Predicted to enable growth factor activity. Acts upstream of or within cell-matrix adhesion and extracellular matrix organization. Predicted to be located in extracellular region. Is expressed in several structures, including articular cartilage; autopod; respiratory system; sensory organ; and skeleton. Orthologous to human MIA (MIA SH3 domain containing). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Mia |
| Official Name | melanoma inhibitory activity [Source:MGI Symbol;Acc:MGI:109615] |
| Ensembl ID | ENSMUSG00000089661 |
| Bio databases IDs | |
| Aliases | melanoma inhibitory activity |
| Synonyms | CD-RAP, LOC100364484, Melanoma inhibitory activity, MIA1, MIA SH3 domain containing |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mia often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Src Homology 3 domain superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- pituitary gland adenoma
- adenoma formation
- head and neck neuroendocrine neoplasia
- senile lentigo
- Kawasaki disease
- squamous-cell carcinoma
- squamous cell cancer
role in cell
- apoptosis
- proliferation
- quantity
- growth
- migration
- adhesion
- G2 phase
- organization
- invasion
- abnormal morphology
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mia gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- extracellular matrix organization
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- growth factor activity