Vsig1 Gene Summary [Mouse]

Acts upstream of or within epithelial cell morphogenesis and maintenance of gastrointestinal epithelium. Located in basolateral plasma membrane. Is expressed in ovary; stomach; stomach glandular epithelium; stomach glandular region epithelium; and testis. Orthologous to human VSIG1 (V-set and immunoglobulin domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Vsig1
Official Name
V-set and immunoglobulin domain containing 1 [Source:MGI Symbol;Acc:MGI:1926039]
Ensembl ID
ENSMUSG00000031430
Bio databases IDs NCBI: 78789 Ensembl: ENSMUSG00000031430
Aliases V-set and immunoglobulin domain containing 1
Synonyms 1700062D20Rik, 4930405J24Rik, AL672306.1, dJ889N15.1, GPA34, V-set and immunoglobulin domain containing 1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Vsig1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Immunoglobulin V-Type
  • immunoglobulin domain
  • Immunoglobulin like
  • Immunoglobulin I-set domain
  • protein binding
  • Immunoglobulin V-set domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Turner syndrome
regulated by
role in cell
  • morphogenesis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • basolateral membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Vsig1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • epithelial cell morphogenesis
  • maintenance of gastrointestinal epithelium

Cellular Component

Where in the cell the gene product is active
  • basolateral plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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