Rhox5 Gene Summary [Mouse]
Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Acts upstream of or within ectopic germ cell programmed cell death; flagellated sperm motility; and regulation of DNA-templated transcription. Located in cytoplasm and nucleus. Is expressed in several structures, including early conceptus; genitourinary system; heart; respiratory system; and vertebral axis musculature. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rhox5 |
| Official Name | reproductive homeobox 5 [Source:MGI Symbol;Acc:MGI:97538] |
| Ensembl ID | ENSMUSG00000095180 |
| Bio databases IDs | |
| Aliases | reproductive homeobox 5 |
| Synonyms | Pem, Placentae And Embryos Oncofetal, reproductive homeobox 5, Rhox homeobox family member 5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rhox5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity
- transcription regulator
- Homeodomain-interacting protein kinase domain
- protein binding
- homeodomain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
- apoptosis
- expression in
- motility
- differentiation
- transcription in
- production
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm