Ndufa7 Gene Summary [Rat]
This gene encodes a subunit of NADH:ubiquinone oxidoreductase (complex I), which is a multiprotein complex located in the inner mitochondrial membrane. Complex I functions in the transfer of electrons from NADH to the respiratory chain. [provided by RefSeq, Mar 2011]
Details
| Type | Protein Coding |
| Official Symbol | Ndufa7 |
| Official Name | NADH:ubiquinone oxidoreductase subunit A7 [Source:RGD Symbol;Acc:1304597] |
| Ensembl ID | ENSRNOG00000006939 |
| Bio databases IDs | |
| Aliases | NADH:ubiquinone oxidoreductase subunit A7 |
| Synonyms | 14.5kDa, 2400007M02Rik, B14.5a, CI-B14.5a, NADH:ubiquinone oxidoreductase subunit A7 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ndufa7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
- enzyme
- protein binding
Pathways
Biological processes and signaling networks where the Ndufa7 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ndufa7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transmembrane transport
- mitochondrial electron transport, NADH to ubiquinone
- mitochondrial translation
- aerobic respiration
- mitochondrial ATP synthesis coupled proton transport
Cellular Component
Where in the cell the gene product is active
- respiratory chain complex I
- mitochondrion
- mitochondrial ribosome
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- structural constituent of ribosome
- NADH dehydrogenase (ubiquinone) activity