Timm10 Gene Summary [Rat]

Predicted to enable membrane insertase activity; protein homodimerization activity; and protein-folding chaperone binding activity. Predicted to be involved in protein insertion into mitochondrial inner membrane. Predicted to be located in mitochondrial intermembrane space. Predicted to be part of TIM22 mitochondrial import inner membrane insertion complex and mitochondrial intermembrane space protein transporter complex. Predicted to be active in mitochondrial inner membrane. Orthologous to human TIMM10 (translocase of inner mitochondrial membrane 10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Timm10
Official Name
translocase of inner mitochondrial membrane 10 [Source:RGD Symbol;Acc:621741]
Ensembl ID
ENSRNOG00000007883
Bio databases IDs NCBI: 64464 Ensembl: ENSRNOG00000007883
Aliases translocase of inner mitochondrial membrane 10
Synonyms TIM10, TIM10A, Tim13, TIMM10A, Timm13a, translocase of inner mitochondrial membrane 10
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Timm10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • zinc ion binding
  • protein homodimerization
  • Tim10/DDP family zinc finger
  • protein binding
  • chaperone binding
  • transporter

Pathways

Biological processes and signaling networks where the Timm10 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Sengers syndrome
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • inner membrane
  • Mitochondria
  • mitochondrial intermembrane space
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Timm10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sensory perception of sound
  • protein targeting to mitochondrion
  • protein import into mitochondrial inner membrane

Cellular Component

Where in the cell the gene product is active
  • mitochondrial inner membrane presequence translocase complex
  • mitochondrial intermembrane space
  • mitochondrion
  • mitochondrial intermembrane space protein transporter complex
  • mitochondrial inner membrane protein insertion complex
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • membrane insertase activity
  • protein binding
  • protein homodimerization activity
  • chaperone binding

Gene-Specific Assays for Results You Can Trust

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