Cdh10 Gene Summary [Rat]
Predicted to enable beta-catenin binding activity and cadherin binding activity. Predicted to be involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and cell-cell junction organization. Is active in GABA-ergic synapse; glutamatergic synapse; and synaptic membrane. Orthologous to human CDH10 (cadherin 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cdh10 |
| Official Name | cadherin 10 [Source:RGD Symbol;Acc:619741] |
| Ensembl ID | ENSRNOG00000009771 |
| Bio databases IDs | |
| Aliases | cadherin 10 |
| Synonyms | A830016G23RIK, C030003B10RIK, C030011H18RIK, cadherin 10, T2-cadherin |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cdh10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cadherin, Y-type LIR-motif
- Cadherin repeat-like domain
Pathways
Biological processes and signaling networks where the Cdh10 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- idiopathic scoliosis
- preeclampsia
- myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis
regulates
role in cell
- size
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- presynaptic regions
- postsynaptic region
- cellular membrane
- presynaptic membrane
- synaptic membrane
- synapse
- postsynaptic density
- inhibitory synapse
- excitatory synapses
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cdh10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- calcium-dependent cell-cell adhesion
- cell-cell junction assembly
- adherens junction organization
- multicellular organismal development
- cell-cell adhesion mediated by cadherin
- cell morphogenesis
- homophilic cell adhesion
- cell migration
Cellular Component
Where in the cell the gene product is active
- adherens junction
- catenin complex
- presynaptic active zone membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- calcium ion binding
- cadherin binding
- beta-catenin binding