Aif1l

Predicted to enable actin filament binding activity and calcium ion binding activity. Predicted to be involved in actin filament bundle assembly and ruffle assembly. Predicted to be located in actin cytoskeleton and focal adhesion. Predicted to be part of protein-containing complex. Predicted to colocalize with actin filament and ruffle membrane. Is expressed in several structures, including cranium; male reproductive gland or organ; nervous system; otocyst; and stomach. Orthologous to human AIF1L (allograft inflammatory factor 1 like). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Aif1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Aif1l gene, providing context for its role in the cell.