Mtmr7 Gene Summary [Rat]
Predicted to enable inositol bisphosphate phosphatase activity; phosphatidylinositol-3,5-bisphosphate phosphatase activity; and phosphatidylinositol-3-phosphate phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be located in cytosol and membrane. Predicted to be active in cytoplasm. Orthologous to human MTMR7 (myotubularin related protein 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mtmr7 |
| Official Name | myotubularin related protein 7 [Source:RGD Symbol;Acc:1306608] |
| Ensembl ID | ENSRNOG00000011420 |
| Bio databases IDs | |
| Aliases | myotubularin related protein 7 |
| Synonyms | DJ710L4.2, myotubularin related protein 7 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mtmr7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein-tyrosine-phoshatase
- phosphatidylinositol-3-phosphatase
- inositol bisphosphate phosphatase
- SET binding domain
- phosphatase
- Myotubularin-like phosphatase domain
- coiled-coil domain
- PTP_DSP_cys
- protein binding
- Pleckstrin homology-like domain
Pathways
Biological processes and signaling networks where the Mtmr7 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- insomnia
- spermatocele
- alloxan-induced diabetic nephropathy
- myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis
regulates
- AKT
- phosphatidylinositol
- inositol 1,3-bisphosphate
- phosphatidylinositol-3-phosphate
role in cell
- survival
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane fraction
- perinuclear region
- cellular membrane
- cytosol
- Golgi membrane
- cytosolic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mtmr7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein dephosphorylation
- phosphatidylinositol biosynthetic process
- phosphatidylinositol dephosphorylation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
- endomembrane system
- cytosol
Molecular Function
What the gene product does at the molecular level
- phosphatidylinositol-3-phosphatase activity
- protein binding
- protein tyrosine phosphatase activity
- phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
- inositol bisphosphate phosphatase activity