S100a5 Gene Summary [Rat]

Predicted to enable calcium-dependent protein binding activity; metal ion binding activity; and protein homodimerization activity. Predicted to be located in neuronal cell body. Predicted to be active in nucleus. Orthologous to human S100A5 (S100 calcium binding protein A5). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
S100a5
Official Name
S100 calcium binding protein A5 [Source:RGD Symbol;Acc:1308996]
Ensembl ID
ENSRNOG00000011748
Bio databases IDs NCBI: 295211 Ensembl: ENSRNOG00000011748
Aliases S100 calcium binding protein A5
Synonyms S100 calcium binding protein A5, S100D, S100D9
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat S100a5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • copper ion binding
  • S-100/ICaBP type calcium binding domain
  • zinc ion binding
  • calcium ion binding
  • protein homodimerization
  • EFh
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • hepatocellular carcinoma
  • liver cancer
regulated by
role in cell
  • expression in
  • proliferation
  • killing
  • cytotoxicity
  • cellular infiltration by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • perikaryon

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat S100a5 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • neuronal cell body

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • protein binding
  • protein homodimerization activity
  • copper ion binding
  • calcium ion binding
  • calcium-dependent protein binding

Gene-Specific Assays for Results You Can Trust

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