Ajuba

Predicted to enable several functions, including actin filament binding activity; alpha-catenin binding activity; and transcription corepressor activity. Predicted to be involved in several processes, including regulation of cellular response to hypoxia; regulation of gene expression; and regulation of intracellular signal transduction. Predicted to act upstream of or within several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; regulation of biosynthetic process; and regulation of kinase activity. Located in cell-cell junction. Orthologous to human AJUBA (ajuba LIM protein). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ajuba often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ajuba gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Ajuba gene, providing context for its role in the cell.