Myl2

Predicted to enable actin monomer binding activity and calcium ion binding activity. Predicted to be a structural constituent of muscle. Involved in cardiac muscle contraction; cell growth involved in cardiac muscle cell development; and regulation of the force of heart contraction. Located in myofibril. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy; hypertrophic cardiomyopathy 10; and infantile-onset myofibrillar myopathy 12 with cardiomyopathy. Orthologous to human MYL2 (myosin light chain 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Myl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Myl2 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Myl2 gene, providing context for its role in the cell.