Xpo6 Gene Summary [Rat]

Predicted to enable nuclear export signal receptor activity. Predicted to be involved in protein export from nucleus. Predicted to be located in cytosol; nuclear lumen; and plasma membrane. Predicted to be part of protein-containing complex. Orthologous to human XPO6 (exportin 6). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Xpo6
Official Name
exportin 6 [Source:RGD Symbol;Acc:1311491]
Ensembl ID
ENSRNOG00000016722
Bio databases IDs NCBI: 293476 Ensembl: ENSRNOG00000016722
Aliases exportin 6
Synonyms 2610005L19Rik, C230091E20Rik, EXP6, exportin 6, KIAA0370, LOC100912006, mKIAA0370, RANBP20
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Xpo6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Exportin 1-like protein
  • protein binding
  • Importin-beta N-terminal domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • RASSF1
  • mir-122 (includes others)
  • MIRN1
  • PFN1
  • mir-1 (includes others)
  • Escherichia coli K12
  • profilin
  • topotecan
regulates
role in cell
  • trimethylation in
  • aggregation in
  • dipeptide repeat protein sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane
  • cytosol
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Xpo6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein export from nucleus

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • cytosol
  • macromolecular complex
  • nucleolus
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • small GTPase binding
  • nuclear export signal receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.