Gstm3l Gene Summary [Rat]
Predicted to enable glutathione transferase activity and identical protein binding activity. Predicted to act upstream of or within cellular response to xenobiotic stimulus and response to bacterium. Predicted to be located in cytoplasm. Biomarker of hypertension. [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gstm3l |
| Official Name | glutathione S-transferase mu 3-like [Source:RGD Symbol;Acc:620381] |
| Ensembl ID | ENSRNOG00000019058 |
| Bio databases IDs | |
| Aliases | glutathione S-transferase mu 3-like |
| Synonyms | Fsc2, Glutathione S-Transferase5, glutathione S-transferase mu 3, glutathione S-transferase, mu 3, Glutathione S-transferase, mu 3l, Gst Gt9.3, Gstm3l, Gstm3l1, Gstm4, GstYb4, Gt9.3, mGSTM5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gstm3l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Glutathione S-transferase, C-terminal domain
- Glutathione S-transferase, N-terminal domain
- C-terminal, alpha helical domain of the Glutathione S-transferase family
- binding protein
- glutathione transferase
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- enzyme binding
- protein homodimerization
- enzyme
Pathways
Biological processes and signaling networks where the Gstm3l gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
- glutathione
- 1-chloro-2,4-dinitrobenzene
- trans-4-phenylbut-3-en-2-one
- cumene hydroperoxide
- ethacrynic acid
- 3,4-dichloronitrobenzene
- sulfobromophthalein
- p-nitrophenyl acetate
- 4-nitrobenzyl chloride
- 1,2-epoxy-3-(p-nitrophenoxy)propane
role in cell
- response by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic bridges
- cytosol