Lgals7 Gene Summary [Rat]
Predicted to enable carbohydrate binding activity. Predicted to be involved in apoptotic process. Predicted to be located in cytoplasm; extracellular region; and nucleus. Predicted to be active in cornified envelope. Orthologous to several human genes including LGALS7 (galectin 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lgals7 |
| Official Name | galectin 7 [Source:RGD Symbol;Acc:61951] |
| Ensembl ID | ENSRNOG00000020380 |
| Bio databases IDs | |
| Aliases | galectin 7 |
| Synonyms | GAL7, Galactin7, Galectin-7, HKL-14, lectin, galactose binding, soluble 7, LGALS7A, Pig1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lgals7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GLECT
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- cutaneous melanoma cancer
- albuminuria
- lymphomagenesis
- cutaneous melanoma
- B-cell lymphoma
- B cell cancer
- Ullrich congenital muscular dystrophy
- urothelial carcinoma
- urothelial cancer
role in cell
- apoptosis
- growth
- accumulation in
- expression in
- activation in
- proliferation
- phosphorylation in
- survival
- colony formation
- nuclear export in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- detergent resistant lipid raft fraction
- cornified envelope
- Extracellular Space
- perinuclear region
- Nucleus
- Mitochondria