Lgals7 Gene Summary [Mouse]
Predicted to enable carbohydrate binding activity. Predicted to be involved in apoptotic process. Is active in cornified envelope. Is expressed in maxillary process and upper jaw. Orthologous to human LGALS7 (galectin 7) and LGALS7B (galectin 7B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lgals7 |
| Official Name | lectin, galactose binding, soluble 7 [Source:MGI Symbol;Acc:MGI:1316742] |
| Ensembl ID | ENSMUSG00000053522 |
| Bio databases IDs | |
| Aliases | lectin, galactose binding, soluble 7 |
| Synonyms | GAL7, Galactin7, Galectin-7, HKL-14, lectin, galactose binding, soluble 7, LGALS7A, Pig1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lgals7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GLECT
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- cutaneous melanoma cancer
- albuminuria
- lymphomagenesis
- cutaneous melanoma
- B-cell lymphoma
- B cell cancer
- Ullrich congenital muscular dystrophy
- urothelial carcinoma
- urothelial cancer
role in cell
- apoptosis
- growth
- accumulation in
- expression in
- activation in
- proliferation
- phosphorylation in
- survival
- colony formation
- nuclear export in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- detergent resistant lipid raft fraction
- cornified envelope
- Extracellular Space
- perinuclear region
- Nucleus
- Mitochondria