Slc35a2 Gene Summary [Rat]
Predicted to enable UDP-galactose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and nucleoplasm. Predicted to be active in Golgi membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIm. Orthologous to human SLC35A2 (solute carrier family 35 member A2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc35a2 |
| Official Name | solute carrier family 35 member A2 [Source:RGD Symbol;Acc:2293497] |
| Ensembl ID | ENSRNOG00000024801 |
| Bio databases IDs | |
| Aliases | solute carrier family 35 member A2 |
| Synonyms | CDG2M, CDGX, Had-1, Sfc8, solute carrier family 35 member A2, Solute carrier family 35 (UDP-galactose transporter), member 2, solute carrier family 35 (UDP-galactose transporter), member A2, UDP-Gal-Tr, UGALT, UGAT, UGT, UGT1, UGT2, UGTL |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc35a2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UDP-galactose transporter
- nucleotide-sugar transporter
- EamA-like transporter family
- enzyme
- protein binding
Pathways
Biological processes and signaling networks where the Slc35a2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- nonlesional localization related epilepsy
- congenital disorder of glycosylation type 2m
- congenital disorders of glycosylation
- epilepsy
- intoxication
- X-linked complex neurodevelopmental disorder
- hereditary disorder
- focal cortical dysplasia type I
- infection by HIV-1
- infection by Enterovirus D68
regulates
- bilirubin
- SELE
- UDP-D-galactose
- UMP
- CMP-sialic acid
- Myelin
- 1-naphthol
- AMP
- UDP-N-acetyl-D-galactosamine
- galactosylceramide
role in cell
- binding
- phagocytosis
- phagocytosis by
- dipeptide repeat protein sensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi Apparatus
- Endoplasmic Reticulum
- Golgi membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Slc35a2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- UDP-galactose transmembrane transport
- galactose metabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endoplasmic reticulum
- Golgi membrane
- Golgi apparatus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- UDP-galactose transmembrane transporter activity
- protein binding
- antiporter activity