Relt Gene Summary [Rat]
Predicted to be involved in amelogenesis and apoptotic process. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 3C. Orthologous to human RELT (RELT TNF receptor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Relt |
| Official Name | RELT, TNF receptor [Source:RGD Symbol;Acc:1305381] |
| Ensembl ID | ENSRNOG00000025075 |
| Bio databases IDs | |
| Aliases | RELT, TNF receptor |
| Synonyms | AI3C, E430021K24Rik, RELT TNF receptor, RELT, TNF receptor, RELT tumor necrosis factor receptor, RELT tumour necrosis factor receptor, TNFRSF19L, TRLT |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Relt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TNFR/NGFR cysteine-rich region
- protein binding
- Tumor necrosis factor receptor superfamily (TNFRSF)
- transmembrane receptor
- Tumour necrosis factor receptor superfamily member 19
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- amelogenesis imperfecta type IIIC
- amelogenesis imperfecta
- Ullrich congenital muscular dystrophy
regulates
- NFkB (complex)
role in cell
- proliferation
- apoptosis
- abnormal morphology
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Relt gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- apoptotic process
- amelogenesis
Cellular Component
Where in the cell the gene product is active
- perinuclear region of cytoplasm
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding