Aspscr1 Gene Summary [Rat]
Predicted to be involved in glucose homeostasis; intracellular protein transport; and positive regulation of protein modification process. Predicted to act upstream of or within regulation of D-glucose import. Predicted to be located in several cellular components, including cytoplasmic side of plasma membrane; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be active in cytoplasm; nucleus; and vesicle membrane. Human ortholog(s) of this gene implicated in alveolar soft part sarcoma. Orthologous to human ASPSCR1 (ASPSCR1 tether for SLC2A4, UBX domain containing). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Aspscr1 |
| Official Name | ASPSCR1 tether for SLC2A4, UBX domain containing [Source:RGD Symbol;Acc:1588666] |
| Ensembl ID | ENSRNOG00000036678 |
| Bio databases IDs | |
| Aliases | ASPSCR1 tether for SLC2A4, UBX domain containing |
| Synonyms | 1190006K01Rik, AB039977, ASPC, ASPCR1, ASPL, ASPS, ASPSCR, ASPSCR1 tether for SLC2A4, UBX domain containing, LOC100131505, LOC688313, RCC17, TUG, UBXD9, UBXN9 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Aspscr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TUG ubiquitin-like domain
- Ubl1_cv_Nsp3_N-like
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- weight loss
- restless legs syndrome
- alveolar soft part sarcoma
- soft tissue sarcoma cancer
- insomnia
role in cell
- production in
- proliferation
- migration
- growth
- exocytosis by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic vesicle membrane
- intracellular membrane-bounded organelle
- perinuclear region
- Plasma Membrane
- cytosol
- cytoplasmic face of plasma membrane
- vesicle membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Aspscr1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glucose homeostasis
- regulation of glucose import
- intracellular protein transport
- positive regulation of protein modification process
Cellular Component
Where in the cell the gene product is active
- nucleus
- perinuclear region of cytoplasm
- cytoplasm
- vesicle membrane
- intracellular membrane-bounded organelle
- endomembrane system
- cytosol
- plasma membrane
- nucleoplasm
- internal side of plasma membrane
- endoplasmic reticulum-Golgi intermediate compartment membrane
Molecular Function
What the gene product does at the molecular level
- protein binding