St6gal2 Gene Summary [Rat]

Predicted to enable beta-galactoside alpha-2,6-sialyltransferase activity. Predicted to be involved in oligosaccharide metabolic process and sialylation. Predicted to be located in Golgi cisterna membrane. Predicted to be active in Golgi apparatus. Orthologous to human ST6GAL2 (ST6 beta-galactoside alpha-2,6-sialyltransferase 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
St6gal2
Official Name
ST6 beta-galactoside alpha-2,6-sialyltransferase 2 [Source:RGD Symbol;Acc:1559663]
Ensembl ID
ENSRNOG00000046515
Bio databases IDs NCBI: 301155 Ensembl: ENSRNOG00000046515
Aliases ST6 beta-galactoside alpha-2,6-sialyltransferase 2
Synonyms beta galactoside alpha 2,6 sialyltransferase 2, C230064G14Rik, LOC100129665, mKIAA1877, SIAT2, ST6 beta-galactoside alpha-2,6-sialyltransferase 2, ST6Gal-II, ST6 β-galactoside α-2,6-sialyltransferase 2, β galactoside α 2,6 sialyltransferase 2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat St6gal2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Glycosyltransferase family 29 (sialyltransferase)
  • beta-galactoside alpha-2,6-sialyltransferase
  • glycosyltransferase family 29
  • sialyltransferase
  • enzyme
  • protein binding
  • monosialoganglioside sialyltransferase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • small cell lung cancer
regulated by
  • mir-30 (includes others)
regulates
role in cell
  • apoptosis
  • oligomerization in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi-enriched fraction
  • Golgi membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat St6gal2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein glycosylation
  • oligosaccharide metabolic process

Cellular Component

Where in the cell the gene product is active
  • Golgi cisterna membrane
  • Golgi membrane
  • Golgi apparatus

Molecular Function

What the gene product does at the molecular level
  • beta-galactoside alpha-2,6-sialyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.