Ppp1r3d Gene Summary [Rat]

Enables enzyme binding activity. Contributes to phosphoprotein phosphatase activity. Involved in regulation of glycogen biosynthetic process and regulation of glycogen catabolic process. Located in glycogen granule. Orthologous to human PPP1R3D (protein phosphatase 1 regulatory subunit 3D). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ppp1r3d
Official Name
protein phosphatase 1, regulatory subunit 3D [Source:RGD Symbol;Acc:1586306]
Ensembl ID
ENSRNOG00000053869
Bio databases IDs NCBI: 689995 Ensembl: ENSRNOG00000053869
Aliases protein phosphatase 1, regulatory subunit 3D
Synonyms 2610024M03RIK, Gm359, LOC682185, PPP1R6, protein phosphatase 1 regulatory subunit 3D, protein phosphatase 1, regulatory subunit 3D, R6
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ppp1r3d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Starch/carbohydrate-binding module (family 53)
  • Carbohydrate/starch-binding module (family 21)
  • protein serine/threonine phosphatase
  • protein phosphatase
  • phosphoprotein phosphatase
  • phosphatase
  • enzyme binding
  • protein binding
  • PBD_PPP1R3

Pathways

Biological processes and signaling networks where the Ppp1r3d gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • uterine leiomyoma
  • leiomyomatosis
regulated by
  • tetradecanoylphorbol acetate
  • PRKCD
  • camptothecin
  • FAS
  • neutrophils
  • ADP
  • CPT1B
regulates
  • insulin
  • glycogen
  • PP1
  • glycogen synthase
role in cell
  • survival

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ppp1r3d gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • glycogen metabolic process
  • regulation of glycogen biosynthetic process
  • regulation of glycogen catabolic process

Cellular Component

Where in the cell the gene product is active
  • protein phosphatase type 1 complex
  • glycogen granule

Molecular Function

What the gene product does at the molecular level
  • protein serine/threonine phosphatase activity
  • protein binding
  • protein phosphatase 1 binding
  • glycogen binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.