Cpt1b Gene Summary [Rat]
Enables carnitine O-palmitoyltransferase activity. Involved in carnitine metabolic process; fatty acid metabolic process; and long-chain fatty acid transport. Located in mitochondrion. Orthologous to human CPT1B (carnitine palmitoyltransferase 1B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cpt1b |
| Official Name | carnitine palmitoyltransferase 1B [Source:RGD Symbol;Acc:2397] |
| Ensembl ID | ENSRNOG00000010438 |
| Bio databases IDs | |
| Aliases | carnitine palmitoyltransferase 1B |
| Synonyms | carnitine palmitoyltransferase 1B, carnitine palmitoyltransferase 1b, muscle, carnitine palmitoyl transferase I, CPT1, CPT1-M, Cpt1 β, CPTI, CPT-IB, CPTI-M, Cpt i β, MCCPT1, M-CPT1, M-CPTI |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cpt1b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Choline/Carnitine o-acyltransferase
- carnitine O-palmitoyltransferase
- enzyme
- protein binding
- Carnitine O-palmitoyltransferase N-terminus
Pathways
Biological processes and signaling networks where the Cpt1b gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- myelodysplastic syndrome
- lung adenocarcinoma
- lung adenocarcinoma formation
- colorectal cancer
- Huntington disease
- chronic myeloid leukemia
- polycystic kidney disease
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial intermembrane space
- mitochondrial outer membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cpt1b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fatty acid beta-oxidation
- long-chain fatty acid transport
- carnitine shuttle
- response to blue light
- carnitine metabolic process
- fatty acid metabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- carnitine O-palmitoyltransferase activity