Cdh8

Predicted to enable beta-catenin binding activity; cadherin binding activity; and identical protein binding activity. Predicted to be involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and cell-cell junction organization. Predicted to act upstream of or within glutamatergic synaptic transmission and response to cold. Predicted to be located in plasma membrane. Predicted to be part of catenin complex. Predicted to be active in several cellular components, including adherens junction; glutamatergic synapse; and synaptic cleft. Orthologous to human CDH8 (cadherin 8). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cdh8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Cdh8 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Cdh8 gene, providing context for its role in the cell.