Rab11fip1 Gene Summary [Rat]
Predicted to enable small GTPase binding activity. Predicted to be involved in negative regulation of adiponectin secretion and regulated exocytosis. Predicted to be located in cytosol. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human RAB11FIP1 (RAB11 family interacting protein 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rab11fip1 |
| Official Name | RAB11 family interacting protein 1 [Source:RGD Symbol;Acc:1562965] |
| Ensembl ID | ENSRNOG00000058940 |
| Bio databases IDs | |
| Aliases | RAB11 family interacting protein 1 |
| Synonyms | 2010200K21Rik, 4833414G05Rik, NOEL1A, RAB11 family interacting protein 1, RAB11 family interacting protein 1 (class I), RCP, RGD1562965 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rab11fip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rab11 binding domain
- FIP domain
- Rab4 binding domain
- protein binding
- Protein kinase C conserved region 2 (CalB)
- C2 domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- metastasis
- ductal breast carcinoma
- ductal breast cancer
- breast cancer
- chickenpox
role in cell
- expression in
- proliferation
- phosphorylation in
- invasion by
- recycling
- invasion
- tubulation
- haptotaxis
- scattering
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane fraction
- tubular endosomal network
- intracellular membrane-bounded organelle
- perinuclear region
- cellular membrane
- cytosol
- perinuclear space
- perinuclear vesicles
- presynaptic terminals
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rab11fip1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of adiponectin secretion
- protein transport
- regulated secretory pathway
Cellular Component
Where in the cell the gene product is active
- intracellular membrane-bounded organelle
- cytosol
- phagocytic vesicle membrane
- recycling endosome
Molecular Function
What the gene product does at the molecular level
- small GTPase binding