Muc13 Gene Summary [Mouse]
Predicted to enable protein homodimerization activity. Predicted to be involved in maintenance of gastrointestinal epithelium. Predicted to be located in apical plasma membrane; cytosol; and extracellular space. Is expressed in midgut; submandibular duct; and submandibular gland. Orthologous to human MUC13 (mucin 13, cell surface associated). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Muc13 |
| Official Name | mucin 13, epithelial transmembrane [Source:MGI Symbol;Acc:MGI:103190] |
| Ensembl ID | ENSMUSG00000022824 |
| Bio databases IDs | |
| Aliases | mucin 13, epithelial transmembrane |
| Synonyms | 114/A10, 14/A10, DRCC1, LOC102551136, LOC207126, Lrrp, Ly64, Lymphocyte antigen 64, Muc-123, Mucin-13, mucin 13, cell surface associated, mucin 13, epithelial transmembrane, NJ-1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Muc13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SEA domain
- protein homodimerization
- EGF_CA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- colon cancer
- neoplasia
- colorectal cancer
- diabetic nephropathy
- organismal death
- diarrhea
- pancreatic ductal adenocarcinoma
- pancreatic epithelial cancer
- ductal pancreatic cancer
- lung adenocarcinoma
role in cell
- expression in
- adhesion
- phosphorylation in
- quantity
- apoptosis
- invasion by
- G1 phase
- proliferation
- migration
- clustering in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Golgi lumen
- Cytoplasm
- cell surface
- cellular membrane
- vacuole
- Plasma Membrane
- cytosol
- apical membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Muc13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maintenance of gastrointestinal epithelium
Cellular Component
Where in the cell the gene product is active
- extracellular space
- cytosol
- Golgi lumen
- apical plasma membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein homodimerization activity