BZW1 Gene Summary [Human]

Enables RNA binding activity and cadherin binding activity. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
BZW1
Official Name
basic leucine zipper and W2 domains 1 [Source:HGNC Symbol;Acc:HGNC:18380]
Ensembl ID
ENSG00000082153
Bio databases IDs NCBI: 9689 Ensembl: ENSG00000082153
Aliases basic leucine zipper and W2 domains 1, eIF5-mimic protein 2
Synonyms 1200015E15Rik, 5MP2, basic leucine zipper and W2 domains 1, BZAP45, Kiaa0005, mKIAA0005, Nbla10236
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human BZW1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • eIF4-gamma/eIF5/eIF2-epsilon
  • protein binding
  • C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon
  • translation regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • cancer
  • liver cancer
  • preeclampsia
  • severe acute respiratory syndrome
  • non-melanoma skin cancer
regulated by
regulates
role in cell
  • cohesion in
  • molecular cleavage in
  • cohesion

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human BZW1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of translational initiation

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • membrane

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • cadherin binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.