FOXRED2 Gene Summary [Human]
Enables flavin adenine dinucleotide binding activity. Involved in ubiquitin-dependent ERAD pathway. Located in endoplasmic reticulum lumen. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | FOXRED2 |
| Official Name | FAD dependent oxidoreductase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26264] |
| Ensembl ID | ENSG00000100350 |
| Bio databases IDs | |
| Aliases | FAD dependent oxidoreductase domain containing 2, ER flavoprotein associated with degradation |
| Synonyms | A430097D04Rik, D15Bwg0759e, DJ1119A7.3, ERFAD, FAD-dependent oxidoreductase domain containing 2, Gm304, RGD1306763 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FOXRED2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rossmann-fold NAD(P)(+)-binding proteins
- flavin adenine dinucleotide binding
- Pyridine nucleotide-disulphide oxidoreductase
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum lumen
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FOXRED2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
Molecular Function
What the gene product does at the molecular level
- protein binding
- flavin adenine dinucleotide binding
- monooxygenase activity