NKG7 Gene Summary [Human]
Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | NKG7 |
| Official Name | natural killer cell granule protein 7 [Source:HGNC Symbol;Acc:HGNC:7830] |
| Ensembl ID | ENSG00000105374 |
| Bio databases IDs | |
| Aliases | natural killer cell granule protein 7, granule membrane protein 17 |
| Synonyms | 2500004F03Rik, GIG1, GMP-17, natural killer cell granule protein 7, natural killer cell group 7 sequence, p15-TIA-1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NKG7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PMP-22/EMP/MP20/Claudin family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- lysosome
- lysosome membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NKG7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inflammatory response
- positive regulation of inflammatory response
- killing of cells of other organism
- natural killer cell degranulation
- natural killer cell mediated cytotoxicity
- CD4-positive, alpha-beta T cell activation
- natural killer cell mediated cytotoxicity directed against tumor cell target
- defense response to protozoan
Cellular Component
Where in the cell the gene product is active
- cytolytic granule
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding