CRYBG1 Gene Summary [Human]
Predicted to enable carbohydrate binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CRYBG1 |
| Official Name | crystallin beta-gamma domain containing 1 [Source:HGNC Symbol;Acc:HGNC:356] |
| Ensembl ID | ENSG00000112297 |
| Bio databases IDs | |
| Aliases | crystallin beta-gamma domain containing 1, suppression of tumorigenicity 4 |
| Synonyms | AIM1, crystallin beta-gamma domain containing 1, crystallin β-γ domain containing 1, ST4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CRYBG1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ricin-type beta-trefoil lectin domain
- Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins
- Ricin-type beta-trefoil
- Treacher Collins syndrome protein Treacle
- ricin B-type lectin domain, beta-trefoil fold
- Beta/Gamma crystallin
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- psoriasis
- mature T-cell neoplasia
- T-cell non-Hodgkin disease
- nasal type extranodal NK-/T-cell lymphoma
- natural killer cell neoplasia
- exostoses
- stroke
- metastatic colorectal cancer
- incisional hernia
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CRYBG1 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- carbohydrate binding