CSAD Gene Summary [Human]
This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Details
| Type | Protein Coding |
| Official Symbol | CSAD |
| Official Name | cysteine sulfinic acid decarboxylase [Source:HGNC Symbol;Acc:HGNC:18966] |
| Ensembl ID | ENSG00000139631 |
| Bio databases IDs | |
| Aliases | cysteine sulfinic acid decarboxylase, P-selectin cytoplasmic tail-associated protein |
| Synonyms | Csadc, CSD, cysteine sulfinic acid decarboxylase, cysteine sulphinic acid decarboxylase, PCAP |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CSAD often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- sulfoalanine decarboxylase
- AAT_I
- carboxy-lyase
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CSAD gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- L-cysteine catabolic process to taurine
- taurine biosynthetic process
- L-cysteine catabolic process to hypotaurine
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- pyridoxal phosphate binding
- sulfinoalanine decarboxylase activity
- aspartate 1-decarboxylase activity