RPL3L Gene Summary [Human]

This gene encodes a protein that shares sequence similarity with ribosomal protein L3. The protein belongs to the L3P family of ribosomal proteins. Unlike the ubiquitous expression of ribosomal protein genes, this gene has a tissue-specific pattern of expression, with the highest levels of expression in skeletal muscle and heart. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
RPL3L
Official Name
ribosomal protein L3 like [Source:HGNC Symbol;Acc:HGNC:10351]
Ensembl ID
ENSG00000140986
Bio databases IDs NCBI: 6123 Ensembl: ENSG00000140986
Aliases ribosomal protein L3 like
Synonyms 1110057H16Rik, CMD2D, RIBOSOMAL protein L3-LIKE
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RPL3L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ribosomal protein L3
  • structural constituent of ribosome
  • rpl3p
  • RNA binding

Pathways

Biological processes and signaling networks where the RPL3L gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dilated cardiomyopathy type 2D
  • atrial fibrillation
  • cardioembolic stroke
role in cell
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ribosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RPL3L gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of myotube differentiation
  • regulation of striated muscle tissue development
  • translation

Cellular Component

Where in the cell the gene product is active
  • membrane
  • cytosolic large ribosomal subunit
  • ribosome

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

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