SLC30A6 Gene Summary [Human]

This gene encodes a member of a family of proteins that function as zinc transporters. This protein can regulate subcellular levels of zinc in the Golgi and vesicles. Expression of this gene is altered in the Alzheimer's disease brain plaques. [provided by RefSeq, Aug 2016]

Details

Type
Protein Coding
Official Symbol
SLC30A6
Official Name
solute carrier family 30 member 6 [Source:HGNC Symbol;Acc:HGNC:19305]
Ensembl ID
ENSG00000152683
Bio databases IDs NCBI: 55676 Ensembl: ENSG00000152683
Aliases solute carrier family 30 member 6
Synonyms 9530029F08RIK, MST103, MSTP103, Slc30a6 predicted, solute carrier family 30 member 6, solute carrier family 30 (zinc transporter), member 6, ZNT6
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC30A6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • cation diffusion facilitator family transporter
  • protein binding
  • zinc ion transporter
  • Cation efflux family
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • sirolimus
  • lipopolysaccharide
  • Immunoglobulin
  • cisplatin
  • heavy metal
  • SLC30A7
  • N,N,N',N'-tetrakis(2-pyridyl-methyl)ethylenediamine
  • SLC30A5
regulates
role in cell
  • stabilization in
  • cytostasis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • trans Golgi network
  • cytoplasmic vesicles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SLC30A6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • zinc ion transport
  • regulation of zinc ion transport

Cellular Component

Where in the cell the gene product is active
  • Golgi apparatus
  • trans-Golgi network membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • zinc ion transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.