TSPAN18 Gene Summary [Human]
Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TSPAN18 |
| Official Name | tetraspanin 18 [Source:HGNC Symbol;Acc:HGNC:20660] |
| Ensembl ID | ENSG00000157570 |
| Bio databases IDs | |
| Aliases | tetraspanin 18 |
| Synonyms | 2610042G18RIK, 6720430O15, Neuronal Tetraspanin, RGD1560411, tetraspanin 18, TSPAN |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TSPAN18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tetraspanin_LEL
- ion channel binding
- protein binding
- Tetraspanin family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- colorectal cancer
- metastasis
- obstructive sleep apnea
- open-angle glaucoma
- organismal death
- schizophrenia
role in cell
- migration
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cell periphery
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TSPAN18 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inflammatory response
- calcium ion-dependent exocytosis
- establishment of localization in cell
- hemostasis
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding