CDYL2 Gene Summary [Human]
Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CDYL2 |
| Official Name | chromodomain Y like 2 [Source:HGNC Symbol;Acc:HGNC:23030] |
| Ensembl ID | ENSG00000166446 |
| Bio databases IDs | |
| Aliases | chromodomain Y like 2 |
| Synonyms | 1700029M19Rik, 4930453I21Rik, chromodomain protein, Y chromosome-like 2, chromodomain Y-like 2, Gm20194, LOC100504367, PCCP1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CDYL2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Chromatin organization modifier domain
- histone binding
- CHROMO (CHRromatin Organization Modifier) domains and chromo shadow domains
- crotonase-like
- protein binding
- Chromo (CHRromatin organization MOdifier) domain
- Enoyl-CoA hydratase/isomerase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- breast cancer
- neoplasia
- cleft lip
- metastasis
- organismal death
- epithelial cancer
- breast carcinoma
- diabetes mellitus
- hepatocellular carcinoma
- liver cancer
role in cell
- expression in
- activation in
- phosphorylation in
- proliferation
- invasiveness
- mobility
- interaction in
- binding in
- ubiquitination in
- docetaxel resistance
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CDYL2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription corepressor activity
- methylated histone residue binding