NUDT16L1 Gene Summary [Human]
Enables snoRNA binding activity. Involved in negative regulation of double-strand break repair via nonhomologous end joining. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | NUDT16L1 |
| Official Name | nudix hydrolase 16 like 1 [Source:HGNC Symbol;Acc:HGNC:28154] |
| Ensembl ID | ENSG00000168101 |
| Bio databases IDs | |
| Aliases | nudix hydrolase 16 like 1, syndesmos |
| Synonyms | 1110001K21Rik, 5330437I08Rik, nudix hydrolase 16 like 1, SDOS, Syndesmos, TIRR |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NUDT16L1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- snoRNA binding
- protein binding
- NUDIX hydrolase superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NUDT16L1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of double-strand break repair via nonhomologous end joining
- snoRNA catabolic process
- mRNA catabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein homodimerization activity
- RNA binding
- snoRNA binding
- protein binding