CHID1 Gene Summary [Human]
Enables oligosaccharide binding activity. Involved in negative regulation of cytokine production involved in inflammatory response. Located in several cellular components, including late endosome; lysosome; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CHID1 |
| Official Name | chitinase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28474] |
| Ensembl ID | ENSG00000177830 |
| Bio databases IDs | |
| Aliases | chitinase domain containing 1, stabilin-1 interacting chitinase-like protein |
| Synonyms | 3110023E09Rik, Cc1-9, chitinase domain containing 1, GL008, LOC100911881, RGD1308955, SI-CLP |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CHID1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Glycosyl hydrolases family 18
- GH18_chitinase-like
- protein binding
- carbohydrate binding
- Glyco_18 domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- globular structure
- Extracellular Space
- lysosome
- trans Golgi network
- lysosomal compartment
- late endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CHID1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- carbohydrate metabolic process
- innate immune response
- negative regulation of cytokine production involved in inflammatory response
Cellular Component
Where in the cell the gene product is active
- nucleus
- trans-Golgi network
- extracellular space
- extracellular vesicular exosome
- membrane
- late endosome
- endomembrane system
- lysosomal lumen
- extracellular region
- lysosome
Molecular Function
What the gene product does at the molecular level
- oligosaccharide binding
- chitin binding
- protein binding