MCMBP Gene Summary [Human]
This gene encodes a protein which is a component of the hexameric minichromosome maintenance (MCM) complex which regulates initiation and elongation of DNA. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Details
| Type | Protein Coding |
| Official Symbol | MCMBP |
| Official Name | minichromosome maintenance complex binding protein [Source:HGNC Symbol;Acc:HGNC:25782] |
| Ensembl ID | ENSG00000197771 |
| Bio databases IDs | |
| Aliases | minichromosome maintenance complex binding protein |
| Synonyms | 1110007A13Rik, C10orf119, FLJ13081, minichromosome maintenance complex binding protein, RGD1306730 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MCMBP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mini-chromosome maintenance replisome factor
- chromatin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cell junction
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MCMBP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- sister chromatid cohesion
- DNA-dependent DNA replication
Cellular Component
Where in the cell the gene product is active
- nucleus
- cell junction
- cytosol
- MCM complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- chromatin binding