IPO9 Gene Summary [Human]
Enables nuclear import signal receptor activity. Involved in protein import into nucleus. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | IPO9 |
| Official Name | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] |
| Ensembl ID | ENSG00000198700 |
| Bio databases IDs | |
| Aliases | importin 9 |
| Synonyms | 0710008K06Rik, AI845704, Imp9, importin 9, KIAA1192, Ranbp9 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IPO9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone binding
- enzyme binding
- protein binding
- Importin-beta N-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- myocardial infarction
- angina pectoris
- metabolic syndrome X
- post-traumatic stress disorder
role in cell
- expression in
- aggregation in
- endocytosis in
- attachment
- cell spreading
- biogenesis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IPO9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein import into nucleus
- proteasome localization
Cellular Component
Where in the cell the gene product is active
- nuclear envelope
- cytoplasm
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- histone binding
- small GTPase binding