Details

Type
Micro RNA
Official Symbol
MIR135A1
Official Name
microRNA 135a-1 [Source:HGNC Symbol;Acc:HGNC:31520]
Ensembl ID
ENSG00000207926
Bio databases IDs NCBI: 406925 Ensembl: ENSG00000207926
Aliases microRNA 135a-1
Synonyms hsa-mir-135-1, hsa-mir-135-2, hsa-miR-135a, hsa-mir-135a-1, hsa-mir-135a-2, hsa-miR-135b, microRNA 135, microRNA 135-1, microRNA 135-2, microRNA 135a, microRNA 135a-1, microRNA 135a-2, microRNA 135b, MIR135A, Mir135a01, MIR135A1, MIR135A2, MIR135B, Mirn135, MIRN135-1, MIRN135-2, Mirn135a, MIRN135A1, MIRN135A2, MIRN135B, miRNA-135a mimic, Mmu-mir-135, mmu-miR-135a, mmu-mir-135a-1, mmu-mir-135a-2, mmu-miR-135b, pre-miR135a1, pre-miR135a2, pre-miR135b, rno-miR-135a, rno-miR-135b
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MIR135A1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • mRNA 3' UTR binding
  • translation repressor
  • mRNA binding
  • microRNA
  • RNA binding

Pathways

Biological processes and signaling networks where the MIR135A1 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
  • experimental autoimmune encephalomyelitis
  • metastasis
  • mammary neoplasm
  • seizures
  • severe asthma
  • metastatic melanoma
  • metastatic melanoma cancer
  • colorectal adenocarcinoma
  • colorectal carcinomagenesis
regulated by
  • YAP1
  • sirolimus
  • cisplatin
  • perchlorate
  • cigarette smoke
  • MKKS
  • butein
  • sphingosine-1-phosphate
  • ERP29
  • STAT3
role in cell
  • expression in
  • growth
  • cell death
  • quantity
  • activation in
  • invasion by
  • phosphorylation in
  • proliferation
  • migration
  • epithelial-mesenchymal transition

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.