Clec10a Gene Summary [Mouse]
Predicted to enable D-mannose binding activity; fucose binding activity; and pattern recognition receptor activity. Acts upstream of or within connective tissue replacement involved in inflammatory response wound healing. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; hemolymphoid system gland; and liver. Orthologous to human CLEC10A (C-type lectin domain containing 10A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Clec10a |
| Official Name | C-type lectin domain family 10, member A [Source:MGI Symbol;Acc:MGI:96975] |
| Ensembl ID | ENSMUSG00000000318 |
| Bio databases IDs | |
| Aliases | C-type lectin domain family 10, member A |
| Synonyms | CD301, CD301a, CD301b, Clec10a, C-type lectin domain containing 10A, C-type lectin domain family 10, member A, Gal/GalNAc-specific lectin, Lectin 1, macrophage galactose N-acetyl-galactosamine specific lectin 2, M-ASGP-BP-1, Mgl, Mgl1, Mgl2, Mgll, N-Acetylgalactosamine specific to lectin |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Clec10a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Hepatic lectin, N-terminal domain
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
- carbohydrate binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane