Clec10a Gene Summary [Rat]

Predicted to enable D-mannose binding activity; fucose binding activity; and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to act upstream of or within connective tissue replacement involved in inflammatory response wound healing. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC10A (C-type lectin domain containing 10A). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Clec10a
Official Name
C-type lectin domain containing 10A [Source:RGD Symbol;Acc:621158]
Ensembl ID
ENSRNOG00000018715
Bio databases IDs NCBI: 64195 Ensembl: ENSRNOG00000018715
Aliases C-type lectin domain containing 10A
Synonyms CD301, CD301a, CD301b, Clec10a, C-type lectin domain containing 10A, C-type lectin domain family 10, member A, Gal/GalNAc-specific lectin, Lectin 1, macrophage galactose N-acetyl-galactosamine specific lectin 2, M-ASGP-BP-1, Mgl, Mgl1, Mgl2, Mgll, N-Acetylgalactosamine specific to lectin
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Clec10a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Hepatic lectin, N-terminal domain
  • C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  • Lectin C-type domain
  • carbohydrate binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • thrombocytosis
  • doxorubicin induced cardiotoxicity
regulated by
role in cell
  • growth
  • number
  • growth in
  • recruitment

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane

Gene-Specific Assays for Results You Can Trust

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